ASSESSMENT OF ARTERIAL WALL STRUCTURE USING ULTRASOUND RADIO FREQUENCY PROCESSING. COMPARING DRY IMMERSION AND SPACEFLIGHT.
- Paper number
IAC-22,A1,2,7,x71862
- Author
Prof. Philippe ARBEILLE, France
- Coauthor
Mrs. Danielle Greaves, Canada, University of Waterloo
- Coauthor
Dr. Richard Hughson, Canada, University of Waterloo
- Year
2022
- Abstract
Background: Ultrasound radio frequency (RF) was used to quantify changes in structure of the common carotid artery (CCA) wall after four days of dry immersion (DI) and compare with the results obtained after six months of microgravity. The hypothesis was that structural changes in each insonated target will be quantifiable using an ultrasound coefficient of reflectivity (R). Method: The R for anterior and posterior CCA, sternocleidomastoid muscle, intima layer and CCA lumen were calculated from the RF data displayed along 5 vertical ultrasound lines selected in the B mode image. Results: After four days of DI, the R coefficient increased in the posterior wall of the CCA (+15% +/- 10 from pre DI, p < 0.05), while no significant change was observed in the other targets. The observed increase in R with DI was approximately half compared to what was observed after six months of space flight (+34% +/- 14). This difference may be explained by dose response; the dry immersion was only four days in duration. Conclusion: The coefficient of reflectivity (R) may be a useful new marker of tissue-level structural changes, a tool that may provide complementary information alongside previously observed wall thickness and stiffness changes occurring in the CCA. Reference: - Arbeille P, D greaves, D Chaput, A Maillet, R Hughson. Index of Reflectivity of ultrasound radiofrequency signal from the carotid artery wall increases in astronauts after a 6-month spaceflight. Ultrasound Med Biol . 2021. May 14;S0301-5629(21)00149-6. doi: 10.1016/j. ultrasmedbio. 2021.03.028.
- Abstract document
- Manuscript document
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