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  • Effects of Bed Test Rest at Normal and Low Energy Intake on Inflammatory Mediators: Evidence for Inverse Regulation of CRP and PTX3

    Paper number

    IAC-06-A1.2.02

    Author

    Dr. Gianni Biolo, University of Trieste, Italy

    Coauthor

    Dr. Martina Heer, German Aerospace Center (DLR), Germany

    Year

    2006

    Abstract

    The levels of physical activity and of energy intake may affect the inflammatory response. We have evaluated the effects of 14 days of bed rest at normal and low energy intake level on plasma levels and white blood cell expression of inflammatory markers [pro- and anti- inflammatory cytokines, C-reactive protein (CRP) and long pentraxin-3 (PTX3)] and mediators (plasma insulin and leptin levels). Nine healthy young volunteers were studied four times at the end of 14-day periods of bed rest (BR) and of controlled ambulation (AMB) receiving eucaloric (ECD) or low-caloric (about 80

    Abstract document

    IAC-06-A1.2.02.pdf