The antiedematous mechanism in aspects of aerospace medicine.
- Paper number
IAC-08.A1.7.-A2.7.11
- Author
Prof. Rauf Gareev, Institute of Human Physiology, Kazakhstan
- Year
2008
- Abstract
Processes of counteraction of hydration of fabrics (interstitia) include many factors. In number of these factors includes the proved mechanism of return of fiber from interstitia into a blood-groove through a wall of blood capillaries (Gareyev, 2003). This mechanism is connected with adsorption-transport function of erythrocytes (Gareyev, 1999). Data are obtained that the arterial-venous difference in quantity of the protein and the glucose, adsorbed on erythrocytes, varies on various physical stress and repeatedly at cosmonauts in day of a landing. Over glucose in experiment this difference is positive correlation always. It shows transferring into tissue from blood a part of glucose adsorbed on erythrocytes. The protein is adsorbed basically on an erythrocytes surface in exchange on the discharged glucose .The gradient of concentration of protein at a level of a venous part of capillaries is moving. Accordingly return of protein from interstitia in blood through the most pervious wall of microcirculation channels is increasing. This mechanism is strengthened by known increase of erythrocytes volume (accordingly, and the areas of adsorption) when they is saturated by carbon dioxide. Assimilation of glucose and saturation of erythrocytes by carbon dioxide directly are connected with an energy metabolism. The concept about this mechanism of return of protein from interstitia into blood-groove through a wall of blood capillaries proves to be true known data about more frequent occurrence of edema during diabetes, hypothyrosis, hypoproteinemia, anemia and some other pathology with decreases of adsorption of protein on an erythrocytes surface or an energy metabolism in tissue. The above-stated data it is necessary to consider for development of actions for reduction of partial edema of tissue for cosmonauts
- Abstract document
- Manuscript document
IAC-08.A1.7.-A2.7.11.pdf (🔒 authorized access only).
To get the manuscript, please contact IAF Secretariat.