rootbrowseIAC-18A1session 44. Medicine in Space and Extreme EnvironmentsPapers1. International cooperation in solving the medical and biological issues of space explorations missions2. dynamic loading, vertebral body fluid and endplate deformation3. Developing telesurgery-teleanesthesia protocols with simulation-based telementoring in remote and extreme environments and feasibility in integrating 3D printed surgical tools, VRAR immersion to train non-medical analog astronauts4. Reduced Parasympathetic Outflow During Overwintering in Antarctica5. A Mars Analog mission; A medical perspective6. Changes in Functional Brain Activation after 30 Days of Isolation and Confinement7. Effects of 30 days confinement on heart rate variability in the Human Exploration Research Analog (HERA)8. changes in lumbar vertebral body bone texture as an index of bone microarchitecture in bed rest studies using trabecular bone score (tbs)9. Impact of sleep restriction and fragmentation on objective and subjective sleep quality – an intervention study10. impact of an extended stay in antarctica on muscle and bone health – first results from the concordia research station11. FROM ANTARCTICA TO ALZHEIMERS – EXERCISE HELPS TO PREVENT COGNITIVE DECLINE12. Cardiac autonomic modulation as a tool to predict performance in a 100 km ultramarathon13. Spatio-temporal visualization of Big Data analytics during spaceflight14. Influence of short-term isolation in a hermetically closed facility on the dynamics of metabolic regulation markers and parameters characterizing the state of bone tissue and body composition of volunteers ( «LUNA-2015» and «SIRIUS-17»)14. Peripheral blood dendritic cells in crew members of the “SIRIUS-17”15. 3D Regional Differentiated Bone Remodeling Monitoring at the Proximal Femur before, during 60 Days Bed Rest and One Year Follow-Up after Using Reactive Jump Exercises as Countermeasure for Avoiding Loss of Bone Mass16. Dysregulation of the circadian clock by external factors disrupts cellular processes and impacts in physiology and human health17. Medical practitioners in extreme environments: a review of selection criteria and desirable skills for isolated doctors18. Dental Health for long-term Human Space Missions with remote support and advanced technology19. HypoCampus - Hippocampal Plasticity and Spatial Navigation on the ISS20. Acute effects of physical exercise on cognitive performance in simulated weightlessness by full water immersion21. Cardiac and Psychological Measurements during an Ultramarathon in Cold Climate22. Mathematical modelling of the circadian core-clock can be used to characterise the temporal profile of human cells and to simulate the impact of circadian dysregulations.